Southern Indiana Vacations from $437

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to $2,000 when you book a flight and hotel together*
  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
  • Rest easy

    Plan, book, and manage your trip all in one place

Your Southern Indiana Vacation

Make planning your next big adventure a breeze with a Southern Indiana vacation package. Whether it's nature, history or something else that draws you here, our packages will help you discover it all. A trip to Southern Indiana wouldn't be complete without exploring some of its leading cities, starting with Louisville. A couple of the most popular attractions here include KFC Yum Center and Kentucky Kingdom. Evansville is another favorite with Southern Indiana travelers. Visitors to this destination enjoy Ford Center and Bally's Evansville Casino. When you're ready to stop daydreaming and start doing, Expedia will help turn your Southern Indiana vacation into a reality.

The Latest Southern Indiana vacation packages

Price found within the past 48 hours. Click for updated prices.
Ashley Quarters Hotel Cincinnati Airport
Belterra Casino Resort
Holiday Inn Express Hotel & Suites Richwood-Cincinnati South by IHG
Louisville Marriott Downtown
Graduate by Hilton Cincinnati
Don't see what you're looking for?
See all available trips from Columbus to Southern Indiana
View all trips

Where to stay in Southern Indiana

Find the best Southern Indiana areas and neighborhoods for the activities you enjoy most. Learn more about Southern Indiana

Discover the most popular places to visit in Southern Indiana

Southern Indiana Hotel Deals

Radisson Hotel Louisville North

Radisson Hotel Louisville North

3 out of 5
505 Marriott Drive Clarksville IN
Fully refundableReserve now, pay when you stay
$57 nightly
The price is $65 total per night from May 17 to May 18
$65 total
May 17 - May 18
Total with taxes and fees
7/10 Good! (3,064 reviews)
The towels, sheets, mattresses and pillows are new and well maintained. The view from the window in the rooms of the A wing facing the lake is beautiful. The floors were dirty on all the corners of the room and the first room we were offered had the door broken into and it wouldn’t lock. Staff was ...

Reviewed on May 9, 2026

Radisson Hotel Louisville North
Derby Hotel & Suites

Derby Hotel & Suites

2 out of 5
505 K Marriot Dr Clarksville IN
Fully refundableReserve now, pay when you stay
$61 nightly
The price is $69 total per night from May 18 to May 19
$69 total
May 18 - May 19
Total with taxes and fees
6/10 (42 reviews)
This place is a switch and bait. Picture is for the Radisson in the front and the Derby is an old building attached in the back. Nasty looking and old. Do not believe the picture on the internet. I felt dirty and not safe there. One guy was watching us unload the car and made me uncomfortable. Would ...

Reviewed on May 10, 2026

Derby Hotel & Suites
Bally’s Evansville Casino & Hotel

Bally’s Evansville Casino & Hotel

3 out of 5
421 NW Riverside Drive Evansville IN
Fully refundableReserve now, pay when you stay
$85 nightly
The price is $95 total per night from May 19 to May 20
$95 total
May 19 - May 20
Total with taxes and fees
7.8/10 Good! (1,293 reviews)
Great experience

Reviewed on May 8, 2026

Bally’s Evansville Casino & Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Southern Indiana Vacation Packages

Things to do near Southern Indiana

Southern Indiana offers a delightful blend of outdoor adventures, picturesque scenery, and romantic getaways. Enjoy fun festivals, explore quirky roadside attractions, and visit popular tourism sites. You can indulge in body treatments or splash around at a local water park, making it a perfect destination for relaxation and excitement. Whether you're seeking a quiet retreat or thrilling activities, Southern Indiana has something for everyone.

Shopping

Discover the charming Jasper City Mill, located 10 miles from Southern Indiana, offering unique gifts and local crafts. Just 19 miles away, Antique Shak features a delightful selection of vintage treasures and collectibles, perfect for finding that special souvenir to remember your trip.

Recreation

Sultan's Run Golf Course offers a fantastic golfing experience with its scenic landscapes and challenging holes, perfect for outdoor enthusiasts. Meanwhile, Jim Yellig Park provides a tranquil setting for relaxation and wellness activities, allowing visitors to unwind amid nature. Jasper Municipal Golf Course also invites sports lovers to enjoy its beautiful fairways.

Adventure

The Ray Yellig Memorial Trail, located 21 miles from Southern Indiana, offers an exhilarating hiking experience. Immerse yourself in the breathtaking scenery as you traverse diverse landscapes, perfect for outdoor enthusiasts seeking adventure and a connection with nature.

Nightlife

Experience the vibrant nightlife of Southern Indiana at the lively River City Casino, where gaming and entertainment blend seamlessly. For a laid-back vibe, check out a local brewery like New Albanian Brewing Co., offering craft beers and a cozy atmosphere perfect for unwinding after a day of exploration.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Find the best attractions near Southern Indiana

Southern Indiana is perfect for outdoor and romantic getaways, offering a variety of attractions such as urban parks, visitor centers, and arts centers. Travelers can enjoy cultural experiences, family activities, and scenic views. Be sure to explore local tourist destinations and attractions to fully appreciate the charm of this region.

  • Dubois County Visitors Center: Located 9 miles from Southern Indiana, this center offers a gateway to adventure with its outdoor activities perfect for families. Explore local attractions, get travel tips, and enjoy the warm hospitality that embodies the spirit of Dubois County.
  • Thyen-Clark Cultural Center: Situated 10 miles away, this arts center is a cultural gem showcasing local art and performances. Experience the vibrant community through various exhibitions and events that celebrate the rich artistic heritage of the region.
  • St Joseph's Church: Just 9 miles from Southern Indiana, this historic church is not only a place of worship but also a stunning architectural landmark. Its serene atmosphere and beautiful design invite visitors to reflect and appreciate its cultural significance.

Best time to go to Southern Indiana

The best time to visit Southern Indiana is dependent on what kind of holiday you are seeking. July is its hottest month on average. At this time, visitor numbers are moderately high and weather is mostly sunny with light rain. January is its coolest month on average. At this time, visitor numbers are moderately low and weather is mostly cloudy with light rain.

calendarCalendar MonthtemperatureTemperaturerainPrecipitationmostlyCloudinessoccupationOccupancypricePricing
January33.1°F (0.6000000000000001°C)Light RainMostly CloudyModerately LowSlightly Low
February36.1°F (2.3000000000000003°C)Light RainMostly CloudyModerately LowSlightly Low
March46.2°F (7.9°C)Light RainMostly CloudyAverageSlightly Low
April55.8°F (13.2°C)Light RainMostly SunnyAverageAverage
May64.9°F (18.3°C)Light RainMostly SunnyAverageAverage
June74.3°F (23.5°C)Light RainMostly SunnyModerately HighSlightly High
July77.2°F (25.1°C)Light RainMostly SunnyModerately HighSlightly High
August75.9°F (24.4°C)Light RainMostly SunnyModerately HighSlightly High
September70.0°F (21.1°C)Light RainMostly SunnyAverageAverage
October58.1°F (14.5°C)Light RainMostly SunnyAverageAverage
November45.9°F (7.7°C)Light RainMostly SunnyAverageAverage
December37.8°F (3.2°C)Light RainMostly CloudyModerately LowAverage

Tips to save on your trip to Southern Indiana

  • Combine your flights, hotels and car rentals on Expedia—bundling can result in significant savings.
  • Consider traveling to Southern Indiana during the low season (January to March) for more affordable options.
  • Use the Price per traveler filter on Expedia to find a package deal that suits your budget.
  • Check the VIP Access properties filter to discover outstanding hotels with added member perks at select properties.

Southern Indiana Essential Information

Language
English
Currency
U.S dollars
Closest Airport
Cincinnati - Northern Kentucky Intl. Airport (CVG)

More vacations you might like

Explore a world of travel with Expedia

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.